INDIANAPOLIS -- The injury bug is still haunting the Indianapolis Colts .

Cornerback Marlin Jackson and strong safety Bob Sanders were lost for the season Friday when the team placed them on injured reserve.

Jackson, who missed the second half of the 2008 season after injuring his right knee during practice, suffered an anterior cruciate ligament injury to his left knee during a non-contact drill Wednesday. He had been rehabbing the knee after he was hurt against Seattle on Oct. 4.

Sanders, a two-time Pro Bowler, tore his left bicep against the 49ers last weekend and will need surgery.

Sanders had just returned to the Colts' lineup two weeks ago. He had missed all of training camp and the first five games of the year after undergoing offseason knee surgery. He has missed 40 of 87 games during his injury-plagued, six-year NFL career.